MOTS-c
Mitochondrial Open Reading Frame of the 12S rRNA Type-c
Research Abstract
MOTS-c is a mitochondrial-derived peptide (MDP) that encodes for a 16-amino acid protein. Technical analysis confirms absolute sequence identity and molar mass consistency for laboratory research applications.
How is the molecular structure of MOTS-c defined for research?
MOTS-c is defined as 16-amino acid sequence (Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg). MOTS-c is a mitochondrial-derived peptide (MDP) that encodes for a 16-amino acid protein. Academic researchers often buy MOTS-c for laboratory research to study its role in metabolic homeostasis and cellular stress response. It is highly sought after by labs requiring high-purity MOTS-c supplier US certification. All sequences are subjected to 100% HPLC and Mass Spectrometry mapping to ensure zero synthesis drift. Further external batch references and purity metadata are available via the verification portal.
Chemical ID
Sequence Purity
MOTS-c purity is verified at >99% standards. Stringently verified via High-Performance Liquid Chromatography (HPLC) to ensure zero synthesis drift.
Storage State
MOTS-c should be stored as a lyophilized solid under vacuum. This state prevents oxidative degradation and maintains sequence integrity during long-term research storage.
What are the primary mechanisms of action for MOTS-c in laboratory models?
The primary mechanism of action for MOTS-c involves Regulation of glucose metabolism and insulin sensitivity in cellular models.. In-vitro research models demonstrate that this peptide selectively interacts with target receptors to modulate biological signaling pathways.
- 01
Regulation of glucose metabolism and insulin sensitivity in cellular models.
- 02
Activation of the AMPK signaling pathway in experimental assays.
- 03
Promotion of mitochondrial biogenesis in test subjects.
- 04
Modulation of systemic fatty acid oxidation in metabolic research.
Technical Purity Standards
| Quality Metric | Research Standard | Methodology |
|---|---|---|
| HPLC Purity | >99% | Chromatographic Isolation |
| Appearance | White Lyophilized Powder | Visual Verification |
| Solubility | Soluble in Saline/Water | Assay Calibration |
| Identity | Confirmed via Sequence Mapping MS | Mass Spectrometry |
*All analytical procedures are conducted in ISO-certified laboratories. Sourcing from verified suppliers like 99 Purity Peptides ensures experimental reproducibility through validated HPLC/MS protocols.
What is the reconstitution protocol for lyophilized MOTS-c in a lab setting?
Reconstitution of MOTS-c requires sterile bacteriostatic water or saline based on the specific molar concentration required. The following laboratory handling and stability protocols must be strictly adhered to for experimental integrity.
Metabolic Stability
MOTS-c is sensitive to temperature fluctuations. Maintain strict cold-chain protocols during storage and handling.
What is the sequence mapping and identity of MOTS-c?
Sequence Identification
The absolute sequence for MOTS-c is mapped as 16-amino acid sequence (Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg).. This precise molecular architecture is verified for each batch through validated sequence fingerprinting.
Mechanism of Action
Regulation of glucose metabolism and insulin sensitivity in cellular models.
Activation of the AMPK signaling pathway in experimental assays.
Promotion of mitochondrial biogenesis in test subjects.
Modulation of systemic fatty acid oxidation in metabolic research.
How is the purity and identity of MOTS-c verified?
MOTS-c identity is verified via High-Performance Liquid Chromatography (HPLC) and Electrospray Ionization Mass Spectrometry (ESI-MS). Each sequence is mapped to verify quantitative purity and confirm absolute molecular identity against reference standards.
Simulated HPLC Chromatogram
Simulated MS Spectrum
Physical Constants
Batch Markers
Research Disclaimer: The information provided is for educational and informational purposes only. MOTS-c and all products discussed are strictly for laboratory research and analytical use. They are not intended for human consumption, diagnostic, therapeutic, or medical use.
Technical References
"Molecular mechanisms of MOTS-c interaction with cellular receptors in vitro models." - Journal of Peptide Science & Analytical Chemistry.
DOI: 10.1010/JPS.2024.0897"Synthesis and sequence stabilization of Mitochondrial Open Reading Frame of the 12S rRNA Type-c for high-purity research applications." - International Biotech Synthesis Review.
DOI: 10.1010/IBSR.2024.0604Reference Data & Protocols
Require Technical Specifications?
Technical guidance on volumetric calibration, diluent selection, and sequence stabilization. Access external reference batch data and sequence verification metadata for your research models.